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- 產(chǎn)品名稱:Anti-phospho-Smad1 (Ser187)抗體
- 產(chǎn)品型號:磷酸化細(xì)胞信號轉(zhuǎn)導(dǎo)分子Smad-1抗體
- 產(chǎn)品展商:KALANG
- 產(chǎn)品文檔:無相關(guān)文檔
- 發(fā)布時(shí)間:2018-07-20
- 在線詢價(jià)
簡單介紹
Anti-phospho-Smad1 (Ser187)抗體產(chǎn)品質(zhì)量穩(wěn)定,實(shí)驗(yàn)效果明顯,貨期快,價(jià)格優(yōu)惠,歡迎垂詢訂購!我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-Smad1 (Ser187)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
產(chǎn)品描述
Rabbit Anti-phospho-Smad1 (Ser187)
Cat. Number:
Anti-phospho-Smad1 (Ser187)抗體KL-19917R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila Anti-phospho-Smad1 (Ser187)抗體gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Also known as:
Smad1 (phospho S187); p-Smad1 Anti-phospho-Smad1 (Ser187)抗體(phospho S187); BSP 1; BSP-1; BSP1; Dwarfin A; DwfA; hSMAD 1; hSMAD1; JV 41; JV4 1; JV4-1; JV41; MAD homolog 1; MAD mothers against decapentaplegic homolog 1; Mad related protein 1; Mad-related protein 1; MADH 1; MADH1; Madr 1; MADR1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; Sma and Mad related protein 1; SMA- AND MAD-RELATED PROTEIN 1; SMAD 1; SMAD family member 1; SMAD mothers against DPP homolog 1; SMAD mothers against DPP homolog 1 Drosophila; Smad1; Smad1; SMAD1_HUMAN; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1; Transforming growth factor-beta-signaling protein 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Chicken, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthesised Anti-phospho-Smad1 (Ser187)抗體phosphopeptide derived from human Smad1 around the phosphorylation site of Ser187..
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Predicted Molecular Weight: 52kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-Smad1 (Ser187)抗體
Optimal working dilutions must be determined by the end user.