鼠抗人前列腺特異性抗原單克隆抗體
規(guī)格：1mg/1ml
英文名： PSA (PA5)
別名： antigen, prostate-specific; APS; Gamma seminoprotein; Gamma-seminoprotein; hK3; Kallikrein 3; Kallikrein 3, (prostate specific antigen); Kallikrein related peptidase 3; Kallikrein-3; KLK 3; KLK2A1; KL
分子量： 23kDa
儲存液：0.01M PBS(pH7.4) with 0.03% Proclin300
克隆類型：Monoclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：Full length native protein purified from human
交叉反應(yīng)：Human,
鼠抗人前列腺特異性抗原單克隆抗體細(xì)胞定位：分泌型蛋白
產(chǎn)品介紹：background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. 鼠抗人前列腺特異性抗原單克隆抗體Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. Subunit: Forms heterodimer with SERPINA5. Subcellular Location: Secreted. Tissue Specificity: Prostate. Similarity: Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain. Gene ID: 鼠抗人前列腺特異性抗原單克隆抗體354 Database links: Entrez Gene: 354 Human Omim: 176820 Human SwissProt: P07288 Human Unigene: 171995 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PSA-前列腺特異性抗原為激肽釋放酶家族蛋白，為絲氨酸蛋白酶，由前列腺上皮產(chǎn)生，精液中的濃度很高，可使精液凝塊水解、液化，功能與男性生育力有關(guān). 此抗體可用于試劑盒檢測用抗體。
鼠抗人前列腺特異性抗原單克隆抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Mouse
外觀： Lyophilized or Liquid
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