腫瘤壞死因子α誘導(dǎo)蛋白9/前列腺六跨膜上皮抗原4抗體
規(guī)格:1mg/1ml
英文名: STEAP4
別名: alpha-induced protein 9; Metalloreductase STEAP4; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP 2; STAMP2; STE
分子量: 52kDa
儲(chǔ)存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型:Polyclonal
亞型:IgG
純化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human STEAP4 (
交叉反應(yīng):Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
細(xì)胞定位:細(xì)胞漿 細(xì)胞膜
腫瘤壞死因子α誘導(dǎo)蛋白9/前列腺六跨膜上皮抗原4抗體產(chǎn)品介紹:background: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of腫瘤壞死因子α誘導(dǎo)蛋白9/前列腺六跨膜上皮抗原4抗體 inflammatory cytokines. Inhibits anchorage-independent cell proliferation. Subunit: Interacts with and phosphorylates PTK2/FAK1. Subcellular Location: Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein. Tissue Specificity: Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, 腫瘤壞死因子α誘導(dǎo)蛋白9/前列腺六跨膜上皮抗原4抗體a marker for macrophages. Similarity: Belongs to the STEAP family. Database links: UniProtKB/Swiss-Prot: Q687X5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
腫瘤壞死因子α誘導(dǎo)蛋白9/前列腺六跨膜上皮抗原4抗體產(chǎn)品應(yīng)用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域:腫瘤 **學(xué) 腫瘤細(xì)胞生物標(biāo)志物
儲(chǔ)存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源: Rabbit
外觀: Lyophilized or Liquid
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