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> Recombinant Human OSM, 195a.a.

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Recombinant Human OSM, 195a.a.

Recombinant Human OSM, 195a.a.
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  • 產(chǎn)品名稱:Recombinant Human OSM, 195a.a.
  • 產(chǎn)品型號(hào):
  • 產(chǎn)品展商:XYbscience
  • 產(chǎn)品文檔:無相關(guān)文檔
簡單介紹
Recombinant Human OSM, 195a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋??不會(huì)粘附于管壁。Recombinant Human OSM, 195a.a.所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述

Recombinant Human OSM, 195a.a.

產(chǎn)品編號(hào)

產(chǎn)品名稱

產(chǎn)品包裝

產(chǎn)品價(jià)格

XY363-1mg

Recombinant Human OSM, 195a.a.

1mg

27053.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Human

5008

P13725

E. coli

195aa

22kDa


About this Antibody

Name

Recombinant Human OSM, 195a.a. (Recombinant Human Oncostatin-M, 195a.a.; rHuOSM, 195a.a.);重組人腫瘤抑制素M,195a.a.

Synonyms

MGC20461; oncostatin M; oncostatin-M

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2ng/ml, corresponding to a specific activity of >5.0×105IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 0.1EU/μg of rHuOSM, 195a.a. as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Oncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. The effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant human OSM (195a.a.) has approximately 46% and 45% amino acid sequence identity with rat and murine OSM.

Amino Acid Sequence

AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSR

包裝清單:

產(chǎn)品編號(hào)

產(chǎn)品名稱

包裝

XY363-2μg

Recombinant Human OSM, 195a.a.

2μg

XY363-10μg

Recombinant Human OSM, 195a.a.

10μg

XY363-100μg

Recombinant Human OSM, 195a.a.

100μg

XY363-1mg

Recombinant Human OSM, 195a.a.

1mg

-

說明書

1

保存條件:
       -20℃或更低溫度保存,至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活,所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲(chǔ)存液),須分裝后-20℃或更低溫度凍存,以避免反復(fù)凍融。
注意事項(xiàng):
       由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein,如0.1% BSA)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn),使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲(chǔ)存液。
       本產(chǎn)品**于專業(yè)人員的科學(xué)研究用,不得用于臨床診斷或**,不得用于食品或藥品,不得存放于普通住宅內(nèi)。
       為了您的**和健康,請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。

 

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