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- 產(chǎn)品名稱：Recombinant Human NRG1-β1, 177-241a.a.
- 產(chǎn)品型號(hào)：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Human NRG1-β1, 177-241a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。Recombinant Human NRG1-β1, 177-241a.a.所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述
Recombinant Human NRG1-β1, 177-241a.a.
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價(jià)格
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XY5700-1mg
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Recombinant
Human NRG1-β1, 177-241a.a.
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1mg
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7722.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3084
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Q02297
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E. coli
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65aa
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7.5kDa
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－
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About this
Antibody
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Name
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Recombinant
Human NRG1-β1, 177-241a.a. (Recombinant Human Neuregulin 1-β1 EGF-like domain, 177-241a.a.; rHuNRG1-β1,
177-241a.a.)；重組人神經(jīng)調(diào)節(jié)蛋白1-β1，177-241a.a.
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Synonyms
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GGF; HGL; HRG;
NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using serum free human MCF-7 cells is less than
0.5ng/ml, corresponding to a specific activity of >2.0×106IU/mg.
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Physical
Appearance
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Sterile Filtered
White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered solution in 1X PBS, pH7.4, with 5%
trehalose.
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Endotoxin
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Less than
0.1EU/μg of rHuNRG1-β1, 177-241a.a.
as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Neuregulin 1
(NRG1) is in humans encoded by the NRG1 gene. It is one of four proteins
belonging to the neuregulin family that act on the EGFR family of receptor.
Neuregulin 1 is produced in numerous isoforms by alternative splicing, which
allows it to perform a wide variety of functions. All NRG1 isoforms contain
an EGF like domain (α or β splice variant that
differ in their C terminal region) that is required for their direct binding
to the ErbB3 or ErbB4 receptor tyrosine kinases. NRG1 is necessary for
cardiac development, structural maintenance, and functional integrity of the
heart. NRG1 and its receptor family ErbB can play a beneficial role in the
treatment of chronic heart failure (CHF) by promoting survival of cardiac
myocytes, improving sarcomeric structure, balancing Ca2+homeostasis,
and enhancing pumping function.
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Amino Acid
Sequence
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SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS
RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE
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包裝清單:
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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包裝
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XY5700-10μg
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Recombinant
Human NRG1-β1, 177-241a.a.
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10μg
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XY5700-50μg
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Recombinant
Human NRG1-β1, 177-241a.a.
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50μg
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XY5700-100μg
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Recombinant
Human NRG1-β1, 177-241a.a.
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100μg
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XY5700-1mg
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Recombinant
Human NRG1-β1, 177-241a.a.
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1mg
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-
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說(shuō)明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活，所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液)，須分裝后-20℃或更低溫度凍存，以避免反復(fù)凍融。
注意事項(xiàng):
由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
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