- 如果您對該產(chǎn)品感興趣的話，可以
- 產(chǎn)品名稱：Recombinant Human MIC-A, His-tag
- 產(chǎn)品型號：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無相關文檔
簡單介紹
Recombinant Human MIC-A, His-tag由于有些塑料管壁對某些蛋白有較強的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結合位點，使細???因子或重組蛋白不會粘附于管壁。Recombinant Human MIC-A, His-tag所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
產(chǎn)品描述
Recombinant Human MIC-A, His-tag
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產(chǎn)品編號
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價格
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XY7145-1mg
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Recombinant
Human MIC-A, His-tag
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1mg
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12354.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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100507436
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Q29983
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E. coli
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320aa
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36.9kDa
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His
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About this
Antibody
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Name
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Recombinant
Human MIC-A, His-tag (Recombinant Human MHC Class I PolypeptideRelated
Sequence A, His-tag; rHuMIC-A, His-tag)；重組人MIC類多肽相關序列A，His標簽
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Synonyms
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FLJ60820;
MGC111087; PERB11.1
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The specific activity is
determined by binding MICA antibody in ELISA.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4, and 8
M Urea.
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Endotoxin
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Less than 1EU/μg of rHuMIC-A, His-tag as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water to a concentration of
1.0mg/ml. Stock solutions should be apportioned into working aliquots and
stored at ≤-20℃. Further dilutions should
be made in appropriate buffered solutions, which contain 8M Urea.
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Category
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Others
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Background
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MIC-A (MHC
class I chain-related gene A) is a single-pass type I member protein. It is
expressed on the cell surface in gastric epithelium, endothelial cells and
fibroblasts and in the cytoplasm in keratinocytes and monocytes.
Additionally, MIC-A can be induced by bacterial and viral infections. It
shares 85% amino acid identity with MIC-B and they are distantly related to
the MHC class I proteins. Because they possess three extracellular Ig-like
domains, but unlike classical MHC class I molecules. They do not form a
heterodimer with beta2 microglobulin, but bind as a monomer to a KLRK1/NKG2D
that is an activating receptor expressed on NK cells, NKT cells, γδ T cells, and CD8+ αβ T cells. Recognition of MICA by NKG2D results in the activation
of cytolytic activity and/or cytokine production by these effector cells.
MIC-A recognition plays an important role in tumor surveillance, viral
infections, and autoimmune diseases.
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Amino Acid
Sequence
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MSYYHHHHHH DYDIPTTENL YFQGAMAPEF
EPHSLRYNLT VLSWDGSVQS GFLTEVHLDG QPFLRCDRQK CRAKPQGQWA EDVLGNKTWD RETRDLTGNG
KDLRMTLAHI KDQKEGLHSL QEIRVCEIHE DNSTRSSQHF YYDGELFLSQ NLETKEWTMP QSSRAQTLAM
NVRNFLKEDA MKTKTHYHAM HADCLQELRR YLKSGVVLRR TVPPMVNVTR SEASEGNITV TCRASGFYPW
NITLSWRQDG VSLSHDTQQW GDVLPDGNGT YQTWVATRIC QGEEQRFTCY MEHSGNHSTH PVPSGKVLVL
QSH KLGCFGG
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包裝清單:
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產(chǎn)品編號
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產(chǎn)品名稱
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包裝
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XY7145-10μg
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Recombinant
Human MIC-A, His-tag
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10μg
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XY7145-50μg
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Recombinant
Human MIC-A, His-tag
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50μg
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XY7145-100μg
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Recombinant
Human MIC-A, His-tag
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100μg
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XY7145-1mg
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Recombinant
Human MIC-A, His-tag
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1mg
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-
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說明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會引起部分失活，所以**配制成相應濃度的儲存液后(請根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液)，須分裝后-20℃或更低溫度凍存，以避免反復凍融。
注意事項:
由于有些塑料管壁對某些蛋白有較強的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結合位點，使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
本產(chǎn)品**于專業(yè)人員的科學研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請穿實驗服并戴一次性手套操作。
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