Alanine Racemase (Crude Enzyme)
產(chǎn)品編號(hào)
產(chǎn)品名稱
產(chǎn)品包裝
產(chǎn)品價(jià)格
XY3807-1L
1L
10288.00元
Alanine Racemase，中文名為丙氨酸消旋酶，催化L-丙氨酸與D-丙氨酸之間相互轉(zhuǎn)化。本產(chǎn)品為大腸桿菌表達(dá)的丙氨酸消旋酶，并經(jīng)簡(jiǎn)單純化獲得的可以確保達(dá)到一定酶活力的粗酶液。 由于本產(chǎn)品需新鮮制備，確認(rèn)訂購(gòu)后約6個(gè)工作日才可以發(fā)貨。 本產(chǎn)品可以提供十公斤、百公斤乃至噸級(jí)的粗酶液。 This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. This enzyme participates in alanine and aspartatemetabolism and D-alanine metabolism. It employs one cofactor, pyridoxal phosphate. At least two compounds, 3-Fluoro-D-alanine and D-Cycloserine are known to inhibit this enzyme.The D-alanine produced by alanine racemase is used for peptidoglycan biosynthesis. Peptidoglycan is found in the cell walls of all bacteria, including many which are harmful to humans. The enzyme is absent in higher eukaryotes but found everywhere in prokaryotes, making alanine racemase a great target for antimicrobial drug development.Alanine racemase can be found in some invertebrates.Bacteria can have one (alr gene) or two alanine racemase genes. Bacterial species with two genes for alanine racemase have one that is continually expressed and one that is inducible, which makes it difficult to target both genes for drug studies. However, knockout studies have shown that without the alr gene being expressed, the bacteria would need an external source of D-alanine in order to survive. Therefore, the alr gene is a feasible target for antimicrobial drugs. This product with the indicated enzyme activity was briefly purified from engineered E.coli. 產(chǎn)品詳細(xì)信息見(jiàn)下表:
About this product
Name
Alanine Racemase (Crude Enzyme)；丙氨酸消旋酶(粗酶液)
Application
催化L-丙氨酸與D-丙氨酸之間相互轉(zhuǎn)化
Appearance
Clear to translucent yellow solution
Enzyme activity
Undetermined
About this enzyme
Alanine Racemase；丙氨酸消旋酶
CAS Number
9024-06-0
EC Number
5.1.1.1
Enzymatic Reaction
L-alanine = D-alanine
Synonyms
L-alanine racemase
Systematic name
alanine racemase
Cofactor(s)
pyridoxal 5'-phosphate
drug development; pharmacology; medicine; pharmacology
包裝清單：
包裝
XY3807-100ml
100ml
—
說(shuō)明書
1份
保存條件： -20℃或更低溫度保存，至少1個(gè)月有效。 注意事項(xiàng)： 由于本產(chǎn)品需新鮮制備，在您確認(rèn)訂購(gòu)后約6個(gè)工作日才能發(fā)貨。 粗酶液的每次凍融均可能會(huì)引起部分失活，所以收到酶液后請(qǐng)根據(jù)需要進(jìn)行分裝，并置于-20℃或更低溫度保存。 隨著保存時(shí)間的延長(zhǎng)，酶活力會(huì)有一定程度的下降，收到產(chǎn)品后應(yīng)盡快使用。 本產(chǎn)品在生產(chǎn)和保存的過(guò)程中可能會(huì)有混濁或沉淀產(chǎn)生，融化后混勻即可，不影響正常使用。 本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。 為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。