LRP1 Rabbit Monoclonal Antibody
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產(chǎn)品編號
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價格
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XY1000
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LRP1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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來源
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用途
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交叉反應(yīng)性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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85.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀釋液，可以用于Western檢測或其它適當(dāng)用途時的一抗稀釋。
建議抗體使用時的稀釋比例如下(實(shí)際使用時需根據(jù)抗原水平的高低作適當(dāng)調(diào)整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000-1:5000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:10-1:100
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-
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-
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抗體詳細(xì)信息如下:
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About this
Antibody
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Name
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LRP1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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4035(Human);
16971(Mouse);
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SwissProt
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Q07954(Human);
Q91ZX7(Mouse)
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Synonyms
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APR; LRP;
A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R
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Category
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Metabolism;
Cancer Biology
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Background
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Members of the
LDL receptor gene family, including LDLR (low density lipoprotein receptor),
LRP1 (low density lipoprotein related protein), Megalin (also designated
GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are
characterized by a cluster of cysteine-rich class A repeats, epidermal growth
factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1,
also designated LRP and ?-2-Macroglobulin
receptor, is an endocytic receptor that mediates the uptake of at least 15
ligands, including ?-2-Macroglobulin
and apoE. LRP1 is cleaved into a membrane subunit and an extracellular
subunit, which remain non-covalently associated. Proper folding and trXYficking
of LRP1 is facilitated by the receptor-associated protein (RAP), a molecular
chaperone. The uptake of all known ligands through LRP1 can be blocked by
RAP, which induces a conformational change in the receptor that renders it
unable to bind ligands. LRP1, which is expressed in brain, liver and lung, is
also implicated in Alzheimer's disease (AD), as the human LRP gene localizes
to a potential AD locus on chromosome 12.
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包裝清單:
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產(chǎn)品編號
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產(chǎn)品名稱
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包裝
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XY1000
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LRP1 Rabbit
Monoclonal Antibody
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50μl
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AZ050
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Western一抗稀釋液
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50ml
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-
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說明書
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1份
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保存條件:
LRP1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀釋液-20℃或4℃保存，一年有效。Western一抗稀釋液優(yōu)先推薦4℃保存，長期不使用可以考慮-20℃保存，但凍融可能會導(dǎo)致出現(xiàn)輕微的渾濁和少量不溶物。
注意事項(xiàng):
如果本抗體用于Western blot (WB)、**熒光(IF)、**細(xì)胞化學(xué)(ICC)等實(shí)驗(yàn)，請注意回收使用過的稀釋抗體?；厥盏目贵w通常至少可以重復(fù)使用5-10次。稀釋后的抗體，包括已經(jīng)使用過的稀釋抗體，請4℃保存。
回收后重復(fù)使用的抗體，使用方法同新鮮稀釋的抗體。如果在重復(fù)使用過程中發(fā)現(xiàn)抗體出現(xiàn)輕微混濁現(xiàn)象，可以10,000g離心1-3分鐘，取上清用于后續(xù)檢測。如果回收的抗體出現(xiàn)明顯的絮狀物或長霉長菌等情況，則可以考慮廢棄該抗體。
提供的Western一抗稀釋液也可以用于**熒光(IF)、**組化(IHC)、**細(xì)胞化學(xué)(ICC)等適當(dāng)用途。如果希望獲得*佳的檢測效果，請考慮使用上述檢測專用的一抗稀釋液。
本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請穿實(shí)驗(yàn)服并戴一次性手套操作。
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